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Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines.

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第一作者： Liang,Li

第一单位： Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA. wang.liewei@mayo.edu.

作者： Liang,Li ^[1] ; Brooke L,Fridley ; Krishna,Kalari ; Nifang,Niu ; Gregory,Jenkins ; Anthony,Batzler ; Ryan P,Abo ; Daniel,Schaid ; Liewei,Wang

作者单位： Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA. wang.liewei@mayo.edu. ^[1]

医学主题词细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);阿糖胞苷(Cytarabine);脱氧胞苷(Deoxycytidine);遗传标记(Genetic Markers);全基因组关联研究(Genome-Wide Association Study);基因型(Genotype);人类(Humans);连锁不平衡(Linkage Disequilibrium);甘露糖基转移酶类(Mannosyltransferases);多态性, 单核苷酸(Polymorphism, Single Nucleotide);RNA干扰(RNA Interference);RNA, 小分子干扰(RNA, Small Interfering);调节元件, 转录(Regulatory Elements, Transcriptional)

DOI 10.1186/1471-2164-15-93

PMID 24483146

发布时间 2022-12-07

基金项目

U19 GM61388/GM/NIGMS NIH HHS/United States P50 CA102701/CA/NCI NIH HHS/United States K22 CA130828/CA/NCI NIH HHS/United States R01 CA138461/CA/NCI NIH HHS/United States P30 CA015083/CA/NCI NIH HHS/United States

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