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Optimal translational termination requires C4 lysyl hydroxylation of eRF1.

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第一作者： Tianshu,Feng

第一单位： Centre for Cellular and Molecular Physiology, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK.

作者： Tianshu,Feng ^[1] ; Atsushi,Yamamoto ^[1] ; Sarah E,Wilkins ^[2] ; Elizaveta,Sokolova ^[3] ; Luke A,Yates ^[4] ; Martin,Münzel ^[2] ; Pooja,Singh ^[1] ; Richard J,Hopkinson ^[2] ; Roman,Fischer ^[5] ; Matthew E,Cockman ^[1] ; Jake,Shelley ^[1] ; David C,Trudgian ^[6] ; Johannes,Schödel ^[7] ; James S O,McCullagh ^[2] ; Wei,Ge ^[2] ; Benedikt M,Kessler ^[5] ; Robert J,Gilbert ^[4] ; Ludmila Y,Frolova ^[3] ; Elena,Alkalaeva ^[3] ; Peter J,Ratcliffe ^[1] ; Christopher J,Schofield ^[2] ; Mathew L,Coleman ^[8]

作者单位： Centre for Cellular and Molecular Physiology, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK. ^[1] Chemistry Research Laboratory, Oxford University, 12 Mansfield Road, Oxford OX1 3TA, UK. ^[2] Engelhardt Institute of Molecular Biology, the Russian Academy of Sciences, 119991 Moscow, Russia. ^[3] Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK. ^[4] Target Discovery Institute, Nuffield Department of Medicine, Oxford University, Roosevelt Drive, Oxford OX3 7FZ, UK. ^[5] Biochemistry Department and Proteomics Core, University of Texas Southwestern Medical Center, Dallas, TX 75390-9038, USA. ^[6] Department of Nephrology and Hypertension, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen 91054, Germany. ^[7] Centre for Cellular and Molecular Physiology, Oxford University, Roosevelt Drive, Oxford OX3 7BN, UK. Electronic address: m.coleman@bham.ac.uk. ^[8]