IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone.
第一作者:
Yajun,Chen
第一单位:
Children's National, 111 Michigan Ave NW, Washington, DC 20010. mrose@childrensnational.org.
作者:
主题词
腺癌(Adenocarcinoma);消炎药(Anti-Inflammatory Agents);支气管(Bronchi);细胞, 培养的(Cells, Cultured);染色质免疫沉淀法(Chromatin Immunoprecipitation);cAMP反应元件结合蛋白质(Cyclic AMP Response Element-Binding Protein);指导DNA的RNA聚合酶类(DNA-Directed RNA Polymerases);地塞米松(Dexamethasone);电泳迁移位移试验(Electrophoretic Mobility Shift Assay);基因表达调控(Gene Expression Regulation);人类(Humans);白细胞介素1β(Interleukin-1beta);肺肿瘤(Lung Neoplasms);黏蛋白5AC(Mucin 5AC);NF-κB(NF-kappa B);启动区, 遗传(Promoter Regions, Genetic);RNA, 信使(RNA, Messenger);受体, 白细胞介素1(Receptors, Interleukin-1);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction)
DOI
10.1152/ajplung.00347.2013
PMID
24487386
发布时间
2024-03-23
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