Study designs to investigate Nox1 acceleration of neoplastic progression in immortalized human epithelial cells by selection of differentiation resistant cells.
第一作者:
Apsorn,Sattayakhom
第一单位:
School of Allied Health Sciences and Public Health, Walailak University, Nakhon Si Thammarat, Thailand.
作者:
关键词
AIG, anchorage-independent growthCK, cytokeratinCobblestone cellsCytokeratinsEGF, epidermal growth factorEMTEMT, epithelial mesenchymal transitionGM, gingival mucosalHPV, human papillomavirusIAP, inhibitor of apoptosis proteinImmortalized gingival keratinocytesIntermediate filamentsInvasionMEF2, myocyte enhancing factor 2MMP, matrix metalloproteinasesNox, NAD(P)H oxidasePMA, 12-O- tetradecanoylphorbol-13-acetateROS, reactive oxygen speciesSpindle cellsiNOS, inducible nitric oxide synthase
主题词
细胞分化(Cell Differentiation);细胞系, 转化(Cell Line, Transformed);细胞转化, 肿瘤(Cell Transformation, Neoplastic);疾病恶化(Disease Progression);上皮细胞(Epithelial Cells);上皮-间质转化(Epithelial-Mesenchymal Transition);乙醇(Ethanol);牙龈(Gingiva);人类(Humans);中间丝蛋白质类(Intermediate Filament Proteins);中间丝(Intermediate Filaments);角蛋白18(Keratin-18);肿瘤侵润(Neoplasm Invasiveness);肿瘤蛋白质类(Neoplasm Proteins);癌基因蛋白质类, 病毒性(Oncogene Proteins, Viral);乳头瘤病毒E7蛋白质类(Papillomavirus E7 Proteins);磷酰化(Phosphorylation);蛋白激酶Cε(Protein Kinase C-epsilon);蛋白质加工, 转译后(Protein Processing, Post-Translational);活性氧(Reactive Oxygen Species);阻遏蛋白质类(Repressor Proteins);遗传选择(Selection, Genetic)
DOI
10.1016/j.redox.2013.12.010
PMID
24494188
发布时间
2021-10-21
- 浏览38
Redox biology
2014年2卷
140-7页
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