Convergence in parameters and predictions using computational experimental design.

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作者： David R,Hagen ^[1] ; Jacob K,White ^[2] ; Bruce,Tidor ^[3]

作者单位： Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge, MA 02139 , USA ; Computer Science and Artificial Intelligence Laboratory , Massachusetts Institute of Technology , Cambridge, MA 02139 , USA. ^[1] Department of Electrical Engineering and Computer Science , Massachusetts Institute of Technology , Cambridge, MA 02139 , USA. ^[2] Department of Biological Engineering , Massachusetts Institute of Technology , Cambridge, MA 02139 , USA ; Computer Science and Artificial Intelligence Laboratory , Massachusetts Institute of Technology , Cambridge, MA 02139 , USA ; Department of Electrical Engineering and Computer Science , Massachusetts Institute of Technology , Cambridge, MA 02139 , USA. ^[3]

关键词 Fisher information optimal experimental design ordinary differential equation modelling parameter uncertainty systems biology

DOI 10.1098/rsfs.2013.0008

PMID 24511374

发布时间 2021-10-21

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