The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma.
作者:
主题词
酰基转移酶类(Acyltransferases);动物(Animals);细胞凋亡(Apoptosis);印迹法, 蛋白质(Blotting, Western);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞增殖(Cell Proliferation);细胞转化, 肿瘤(Cell Transformation, Neoplastic);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);免疫酶技术(Immunoenzyme Techniques);同工酶类(Isoenzymes);肺肿瘤(Lung Neoplasms);小鼠(Mice);肿瘤干细胞(Neoplastic Stem Cells);启动区, 遗传(Promoter Regions, Genetic);蛋白激酶C(Protein Kinase C);RNA, 信使(RNA, Messenger);RNA, 小分子干扰(RNA, Small Interfering);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);SOXB1转录因子类(SOXB1 Transcription Factors);信号传导(Signal Transduction);光谱法, 质量, 基质辅助激光解吸电离(Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization);肿瘤细胞, 培养的(Tumor Cells, Cultured)
DOI
10.1016/j.ccr.2014.01.008
PMID
24525231
发布时间
2022-04-09
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Cancer cell
139-51页
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