换一批
换一批The inducible nitric-oxide synthase (iNOS)/Src axis mediates Toll-like receptor 3 tyrosine 759 phosphorylation and enhances its signal transduction, leading to interferon-β synthesis in macrophages.
作者：
主题词
主动转运, 细胞核(Active Transport, Cell Nucleus);动物(Animals);细胞系(Cell Line);细胞核(Cell Nucleus);细胞转化, 病毒(Cell Transformation, Viral);基因表达调控(Gene Expression Regulation);干扰素调节因子3(Interferon Regulatory Factor-3);干扰素调节因子7(Interferon Regulatory Factor-7);干扰素β(Interferon-beta);巨噬细胞, 腹膜(Macrophages, Peritoneal);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);一氧化氮合酶Ⅱ型(Nitric Oxide Synthase Type II);磷酰化(Phosphorylation);原癌基因蛋白质类pp60(c-src)(Proto-Oncogene Proteins pp60(c-src));RNA, 双链(RNA, Double-Stranded);信号传导(Signal Transduction);Toll样受体3(Toll-Like Receptor 3);酪氨酸(Tyrosine)
DOI
10.1074/jbc.M113.508663
PMID
24526685
发布时间
2021-10-21
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