Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcription through histone deacetylase 1 (HDAC1)-mediated histone deacetylation in macrophages.
作者:
主题词
乙酰化作用(Acetylation);动物(Animals);载体蛋白质类(Carrier Proteins);辅阻遏蛋白质类(Co-Repressor Proteins);后成说, 遗传(Epigenesis, Genetic);HEK293细胞(HEK293 Cells);组蛋白脱乙酰基酶1(Histone Deacetylase 1);组蛋白类(Histones);人类(Humans);免疫, 先天(Immunity, Innate);白细胞介素6(Interleukin-6);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);配体(Ligands);脂多糖类(Lipopolysaccharides);巨噬细胞(Macrophages);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);分子伴侣(Molecular Chaperones);核蛋白质类(Nuclear Proteins);启动区, 遗传(Promoter Regions, Genetic);Toll样受体(Toll-Like Receptors);转录, 遗传(Transcription, Genetic);增量调节(Up-Regulation)
DOI
10.1074/jbc.M113.533992
PMID
24550390
发布时间
2021-10-21
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