A protein engineered to bind uranyl selectively and with femtomolar affinity.

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作者： Lu,Zhou ^[1] ; Mike,Bosscher ^[1] ; Changsheng,Zhang ^[2] ; Salih,Ozçubukçu ^[3] ; Liang,Zhang ^[3] ; Wen,Zhang ^[3] ; Charles J,Li ^[3] ; Jianzhao,Liu ^[3] ; Mark P,Jensen ^[4] ; Luhua,Lai ^[5] ; Chuan,He ^[3]

作者单位： 1] Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA [2]. ^[1] 1] BNLMS, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering and Center for Quantitative Biology, Peking University, Beijing 100871, China [2] Center for Life Sciences, Peking University, Beijing 100871, China [3]. ^[2] Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA. ^[3] Chemical Sciences and Engineering Division, Argonne National Laboratory, Argonne, Illinois 60439, USA. ^[4] 1] BNLMS, State Key Laboratory for Structural Chemistry of Unstable and Stable Species, College of Chemistry and Molecular Engineering and Center for Quantitative Biology, Peking University, Beijing 100871, China [2] Center for Life Sciences, Peking University, Beijing 100871, China. ^[5]

主题词结合部位(Binding Sites);金属纳米粒子(Metal Nanoparticles);模型, 分子(Models, Molecular);蛋白质工程(Protein Engineering);蛋白质类(Proteins);铀(Uranium)

DOI 10.1038/nchem.1856

PMID 24557139

发布时间 2021-10-21

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