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Local hyperthermia treatment of tumors induces CD8(+) T cell-mediated resistance against distal and secondary tumors.

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第一作者： Seiko,Toraya-Brown

第一单位： Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755.

作者： Seiko,Toraya-Brown ^[1] ; Mee Rie,Sheen ^[1] ; Peisheng,Zhang ^[1] ; Lei,Chen ^[1] ; Jason R,Baird ^[1] ; Eugene,Demidenko ^[2] ; Mary Jo,Turk ^[3] ; P Jack,Hoopes ^[4] ; Jose R,Conejo-Garcia ^[5] ; Steven,Fiering ^[6]

作者单位： Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755. ^[1] Department of Community and Family Medicine, Geisel School of Medicine at Dartmouth, Hanover, NH03755. ^[2] Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755.;Norris Cotton Cancer Center, Lebanon, NH 03756. ^[3] Department of Surgery, Geisel School of Medicine at Dartmouth, Hanover, NH 03755.;Thayer School of Engineering, Dartmouth College, Hanover, NH 03755.;Norris Cotton Cancer Center, Lebanon, NH 03756. ^[4] Tumor Microenvironment and Metastasis Program, the Wistar Institute, Philadelphia, PA 19104. ^[5] Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, NH 03755.;Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, NH 03755.;Norris Cotton Cancer Center, Lebanon, NH 03756. ^[6]

关键词 Anti-tumor immune Heat Iron oxide Local hyperthermia Nanoparticle

医学主题词动物(Animals);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞系, 肿瘤(Cell Line, Tumor);高温, 诱发(Hyperthermia, Induced);磁性纳米粒子(Magnetite Nanoparticles);小鼠, 近交C57BL(Mice, Inbred C57BL);肿瘤(Neoplasms)

DOI 10.1016/j.nano.2014.01.011

PMID 24566274

发布时间 2022-03-18

基金项目

U54 CA151662/CA/NCI NIH HHS/United States P20 RR016437/RR/NCRR NIH HHS/United States P30 CA010815/CA/NCI NIH HHS/United States P20 RR15639/RR/NCRR NIH HHS/United States P30 CA023108/CA/NCI NIH HHS/United States R01 CA124515/CA/NCI NIH HHS/United States R01 CA157664/CA/NCI NIH HHS/United States 5T32AI007363-22/AI/NIAID NIH HHS/United States 1 U54 CA151662/CA/NCI NIH HHS/United States T32 AI007363/AI/NIAID NIH HHS/United States

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