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Loss of NF1 in cutaneous melanoma is associated with RAS activation and MEK dependence.

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第一作者： Moriah H,Nissan

第一单位： Authors' Affiliations: Louis V. Gerstner, Jr. Graduate School of Biomedical Science; Human Oncology and Pathogenesis Program; Departments of Pediatrics, Pathology, and Medicine; Programs in Molecular Pharmacology and Chemistry; Computational Biology; Ludwig Collaborative Lab, Memorial Sloan-Kettering Cancer Center, New York, New York; Department of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles; Departments of Epidemiology and Biostatistics and Medicine, and the Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California.

作者： Moriah H,Nissan ^[1] ; Christine A,Pratilas ; Alexis M,Jones ; Ricardo,Ramirez ; Helen,Won ; Cailian,Liu ; Shakuntala,Tiwari ; Li,Kong ; Aphrothiti J,Hanrahan ; Zhan,Yao ; Taha,Merghoub ; Antoni,Ribas ; Paul B,Chapman ; Rona,Yaeger ; Barry S,Taylor ; Nikolaus,Schultz ; Michael F,Berger ; Neal,Rosen ; David B,Solit

作者单位： Authors' Affiliations: Louis V. Gerstner, Jr. Graduate School of Biomedical Science; Human Oncology and Pathogenesis Program; Departments of Pediatrics, Pathology, and Medicine; Programs in Molecular Pharmacology and Chemistry; Computational Biology; Ludwig Collaborative Lab, Memorial Sloan-Kettering Cancer Center, New York, New York; Department of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles; Departments of Epidemiology and Biostatistics and Medicine, and the Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California. ^[1]