Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function.
第一作者:
Edward P,Chen
第一单位:
Institute for Translational Medicine and Therapeutics and Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA.
作者:
主题词
动物(Animals);印迹法, 蛋白质(Blotting, Western);细胞转化, 肿瘤(Cell Transformation, Neoplastic);环氧化酶2(Cyclooxygenase 2);女(雌)性(Female);流式细胞术(Flow Cytometry);人类(Humans);免疫酶技术(Immunoenzyme Techniques);整合酶类(Integrases);淋巴细胞活化(Lymphocyte Activation);巨噬细胞(Macrophages);乳房肿瘤, 动物(Mammary Neoplasms, Animal);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);小鼠, 转基因(Mice, Transgenic);髓系细胞(Myeloid Cells);RNA, 信使(RNA, Messenger);受体, 巨噬细胞集落刺激因子(Receptor, Macrophage Colony-Stimulating Factor);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction);光谱法, 质量, 基质辅助激光解吸电离(Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization);T淋巴细胞, 细胞毒性(T-Lymphocytes, Cytotoxic);肿瘤细胞, 培养的(Tumor Cells, Cultured);肿瘤微环境(Tumor Microenvironment)
DOI
10.1093/carcin/bgu053
PMID
24590894
发布时间
2021-10-21
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Carcinogenesis
1788-97页
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