PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.
第一作者:
Carole,Beck
第一单位:
Poly(ADP-ribosyl)ation and Genome Integrity, Laboratoire d'Excellence Medalis, Equipe labellisée Ligue Nationale Contre Le Cancer, UMR7242, Centre Nationale de la Recherche Scientifique/Université de Strasbourg, Institut de Recherche de l'Ecole de Biotechnologie de Strasbourg, 300 bld. S. Brant, BP10413, 67412 Illkirch, France francoise.dantzer@unistra.fr.
作者:
医学主题词
抗原, 核(Antigens, Nuclear);抗肿瘤药(Antineoplastic Agents);BRCA1蛋白质(BRCA1 Protein);细胞周期蛋白质类(Cell Cycle Proteins);细胞系, 肿瘤(Cell Line, Tumor);DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA解旋酶类(DNA Helicases);DNA结合蛋白质类(DNA-Binding Proteins);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);依托泊甙(Etoposide);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);核蛋白质类(Nuclear Proteins);聚ADP核糖聚合酶类(Poly(ADP-ribose) Polymerases);蛋白质加工, 转译后(Protein Processing, Post-Translational);蛋白质转运(Protein Transport);复制蛋白A(Replication Protein A)
DOI
10.1093/nar/gku174
PMID
24598253
发布时间
2021-10-21
- 浏览38
Nucleic acids research
5616-32页
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