换一批DRE-1/FBXO11-dependent degradation of BLMP-1/BLIMP-1 governs C. elegans developmental timing and maturation.
第一作者：
Moritz,Horn
第一单位：
Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Straße 9b, 50931 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (CECAD), University of Cologne, 50674 Cologne, Germany.
作者：
医学主题词
动物(Animals);印迹法, 蛋白质(Blotting, Western);秀丽新小杆线虫(Caenorhabditis elegans);漂亮新小杆线虫蛋白质类(Caenorhabditis elegans Proteins);细胞分化(Cell Differentiation);表皮(Epidermis);F框蛋白质类(F-Box Proteins);基因表达调控, 发育期(Gene Expression Regulation, Developmental);基因沉默(Gene Silencing);性腺(Gonads);HEK293细胞(HEK293 Cells);人类(Humans);免疫酶技术(Immunoenzyme Techniques);幼虫(Larva);长寿(Longevity);器官特异性(Organ Specificity);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);RNA, 小分子干扰(RNA, Small Interfering);时间因素(Time Factors);转录因子(Transcription Factors);泛素化(Ubiquitination)
DOI
10.1016/j.devcel.2014.01.028
PMID
24613396
发布时间
2021-10-21
基金项目
WT_/Wellcome Trust/United Kingdom
R01 GM057587/GM/NIGMS NIH HHS/United States
R01 GM077201/GM/NIGMS NIH HHS/United States
R03 TW009040/TW/FIC NIH HHS/United States
R21-CA161108/CA/NCI NIH HHS/United States
R21 CA161108/CA/NCI NIH HHS/United States
R01-GM057587/GM/NIGMS NIH HHS/United States
R37 CA076584/CA/NCI NIH HHS/United States
R37-CA076584/CA/NCI NIH HHS/United States
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Developmental cell
697-710页
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