Improving coiled coil stability while maintaining specificity by a bacterial hitchhiker selection system.

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第一作者： Tim,Kükenshöner

第一单位： Molecular Biotechnology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany; Institute for Biology III, University of Freiburg, Freiburg im Breisgau, Germany.

作者： Tim,Kükenshöner ^[1] ; Daniel,Wohlwend ^[2] ; Christoph,Niemöller ^[3] ; Padmarupa,Dondapati ^[1] ; Janina,Speck ^[1] ; Adebola V,Adeniran ^[1] ; Anita,Nieth ^[4] ; Stefan,Gerhardt ^[2] ; Oliver,Einsle ^[5] ; Kristian M,Müller ^[6] ; Katja M,Arndt ^[7]

作者单位： Molecular Biotechnology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany; Institute for Biology III, University of Freiburg, Freiburg im Breisgau, Germany. ^[1] Institute for Biochemistry, University of Freiburg, Freiburg im Breisgau, Germany. ^[2] Institute for Biology III, University of Freiburg, Freiburg im Breisgau, Germany. ^[3] Institute for Biology III, University of Freiburg, Freiburg im Breisgau, Germany; Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Freiburg im Breisgau, Germany; Freiburg Institute for Advanced Studies, University of Freiburg, Freiburg im Breisgau, Germany. ^[4] Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Freiburg im Breisgau, Germany; Freiburg Institute for Advanced Studies, University of Freiburg, Freiburg im Breisgau, Germany; Institute for Biochemistry, University of Freiburg, Freiburg im Breisgau, Germany. ^[5] Molecular Biotechnology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany; Institute for Biology III, University of Freiburg, Freiburg im Breisgau, Germany; Cellular and Molecular Biotechnology, Faculty of Technology, Bielefeld University, Germany. ^[6] Molecular Biotechnology, Institute for Biochemistry and Biology, University of Potsdam, Potsdam, Germany; Institute for Biology III, University of Freiburg, Freiburg im Breisgau, Germany; Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Freiburg im Breisgau, Germany; Freiburg Institute for Advanced Studies, University of Freiburg, Freiburg im Breisgau, Germany. Electronic address: katja.arndt@uni-potsdam.de. ^[7]

关键词 Basic helix-loop-helix leucine zipper Coiled coils Microphthalmia associated transcription factor Selection and design Twin arginine translocation pathway