Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood.

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作者： Anjan K,Bongoni ^[1] ; David,Kiermeir ; Hansjörg,Jenni ; Andrea,Bähr ; David,Ayares ; Nikolai,Klymiuk ; Eckhard,Wolf ; Esther,Voegelin ; Mihai A,Constantinescu ; Jörg D,Seebach ; Robert,Rieben

作者单位： Department of Clinical Research, University of Bern, Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland; Clinic of Plastic and Hand Surgery, University Hospital, Bern, Switzerland. ^[1]

关键词 HLA-E apoptosis complement endothelial cells hCD46 pig-to-human xenotransplantation transgenic pig

主题词动物(Animals);动物, 基因修饰(Animals, Genetically Modified);细胞凋亡(Apoptosis);输血(Blood Transfusion);补体系统蛋白质类(Complement System Proteins);细胞因子类(Cytokines);基因敲除技术(Gene Knockout Techniques);遗传标记(Genetic Markers);移植物排斥(Graft Rejection);组织相容性抗原Ⅰ类(Histocompatibility Antigens Class I);人类(Humans);原位缺口末端标记(In Situ Nick-End Labeling);猪(Swine);移植, 异种(Transplantation, Heterologous);血管细胞黏附分子1(Vascular Cell Adhesion Molecule-1)

DOI 10.1111/xen.12090

PMID 24635052

发布时间 2023-12-13

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Xenotransplantation

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Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood.

Xenotransplantation

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Xenotransplantation

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Complement dependent early immunological responses during ex vivo xenoperfusion of hCD46/HLA-E double transgenic pig forelimbs with human blood.

Xenotransplantation

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Xenotransplantation

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