BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups.
第一作者:
Marie-Luise,Berres
第一单位:
Department of Oncological Sciences, 2 Tisch Cancer Institute, and 3 Immunology Institute, Mount Sinai School of Medicine, New York, NY 10029.
作者:
主题词
动物(Animals);抗原, CD34(Antigens, CD34);抗原, 表面(Antigens, Surface);骨髓(Bone Marrow);细胞分化(Cell Differentiation);细胞谱系(Cell Lineage);儿童(Child);儿童, 学龄前(Child, Preschool);树突细胞(Dendritic Cells);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);造血干细胞(Hematopoietic Stem Cells);组织细胞增多症, 郎格尔汉斯细胞(Histiocytosis, Langerhans-Cell);组织相容性抗原Ⅱ类(Histocompatibility Antigens Class II);人类(Humans);婴儿(Infant);外源凝集素类, C型(Lectins, C-Type);男(雄)性(Male);甘露糖结合凝集素类(Mannose-Binding Lectins);小鼠(Mice);突变(Mutation);表型(Phenotype);原癌基因蛋白质B-raf(Proto-Oncogene Proteins B-raf);危险因素(Risk Factors);治疗结果(Treatment Outcome)
DOI
10.1084/jem.20130977
PMID
24638167
发布时间
2022-04-08
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