Tor-Sch9 deficiency activates catabolism of the ketone body-like acetic acid to promote trehalose accumulation and longevity.
第一作者:
Jia,Hu
第一单位:
Longevity Institute, Davis School of Gerontology, University of Southern California, Los Angeles, CA, 90089, USA; Department of Biological Sciences, School of Dornsife College of Letters, Arts and Sciences, University of Southern California, Los Angeles, CA, 90089, USA.
作者:
医学主题词
醋酸(Acetic Acid);人类(Humans);长寿(Longevity);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);蛋白激酶类(Protein Kinases);酿酒酵母菌(Saccharomyces cerevisiae);酿酒酵母蛋白质类(Saccharomyces cerevisiae Proteins);海藻糖(Trehalose)
DOI
10.1111/acel.12202
PMID
24649827
发布时间
2021-10-21
- 浏览31
Aging cell
457-67页
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