A novel functional TagSNP Rs7560488 in the DNMT3A1 promoter is associated with susceptibility to gastric cancer by modulating promoter activity.
作者:
主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);衰老(Aging);等位基因(Alleles);碱基序列(Base Sequence);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);疾病遗传易感性(Genetic Predisposition to Disease);人类(Humans);男(雄)性(Male);中年人(Middle Aged);多态性, 单核苷酸(Polymorphism, Single Nucleotide);启动区, 遗传(Promoter Regions, Genetic);胃肿瘤(Stomach Neoplasms);转录因子AP-1(Transcription Factor AP-1);转录, 遗传(Transcription, Genetic);青年人(Young Adult)
DOI
10.1371/journal.pone.0092911
PMID
24667323
发布时间
2024-11-04
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