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首页> Gynecologic oncology> CGRRF1 as a novel biomarker of tissue response to metformin in the context of obesity.

CGRRF1 as a novel biomarker of tissue response to metformin in the context of obesity.

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第一作者： Qian,Zhang

第一单位： Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

作者： Qian,Zhang ^[1] ; Rosemarie,Schmandt ^[1] ; Joseph,Celestino ^[1] ; Adrienne,McCampbell ^[2] ; Melinda S,Yates ^[1] ; Diana L,Urbauer ^[3] ; Russell R,Broaddus ^[2] ; David S,Loose ^[4] ; Gregory L,Shipley ^[4] ; Karen H,Lu ^[5]

作者单位： Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. ^[1] Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. ^[2] Department of Biostatistics, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. ^[3] Department of Integrative Biology and Pharmacology, The University of Texas Medical School at Houston, Houston, TX 77030, USA. ^[4] Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: khlu@mdanderson.org. ^[5]

关键词 Estrogen Insulin resistance Metformin Obesity

主题词动物(Animals);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);子宫内膜增生(Endometrial Hyperplasia);子宫内膜肿瘤(Endometrial Neoplasms);子宫内膜(Endometrium);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);二甲双胍(Metformin);肥胖症(Obesity);RNA, 信使(RNA, Messenger);大鼠(Rats);大鼠, Zucker(Rats, Zucker);逆转录聚合酶链反应(Reverse Transcriptase Polymerase Chain Reaction)

DOI 10.1016/j.ygyno.2013.12.006

PMID 24680596

发布时间 2021-10-21

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Gynecologic oncology

Gynecologic oncology

2014年133卷1期

83-9页

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