Guggulsterone of Commiphora mukul resin reverses drug resistance in imatinib-resistant leukemic cells by inhibiting cyclooxygenase-2 and P-glycoprotein.
第一作者:
Hong-Bin,Xu
第一单位:
Department of Clinical Pharmacy, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China. Electronic address: xuhongbin@tongji.edu.cn.
作者:
医学主题词
抗肿瘤药, 植物(Antineoplastic Agents, Phytogenic);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);细胞凋亡(Apoptosis);苯甲酰胺类(Benzamides);没药属(Commiphora);环氧化酶2(Cyclooxygenase 2);环氧化酶2抑制剂(Cyclooxygenase 2 Inhibitors);地诺前列酮(Dinoprostone);抗药性, 肿瘤(Drug Resistance, Neoplasm);融合蛋白质类, bcr-abl(Fusion Proteins, bcr-abl);人类(Humans);K562细胞(K562 Cells);哌嗪类(Piperazines);孕烯二酮类(Pregnenediones);嘧啶类(Pyrimidines)
DOI
10.1016/j.phymed.2014.02.014
PMID
24680616
发布时间
2018-12-02
- 浏览95
Phytomedicine
1004-9页
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