Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.-论文-万方医学网

第一作者： J,Bertacchini

第一单位： 1] Department of Surgery, Medicine, Dentistry and Morphology, University of Modena and Reggio Emilia, Modena, Italy [2] Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.

作者： J,Bertacchini ^[1] ; M,Guida ^[2] ; B,Accordi ^[3] ; L,Mediani ^[2] ; A M,Martelli ^[4] ; P,Barozzi ^[5] ; E,Petricoin ^[6] ; L,Liotta ^[6] ; G,Milani ^[3] ; M,Giordan ^[3] ; M,Luppi ^[5] ; F,Forghieri ^[5] ; A,De Pol ^[2] ; L,Cocco ^[4] ; G,Basso ^[3] ; S,Marmiroli ^[2]

作者单位： 1] Department of Surgery, Medicine, Dentistry and Morphology, University of Modena and Reggio Emilia, Modena, Italy [2] Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. ^[1] Department of Surgery, Medicine, Dentistry and Morphology, University of Modena and Reggio Emilia, Modena, Italy. ^[2] Department of Woman's and Child's Health, University of Padova, Padova, Italy. ^[3] Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy. ^[4] Section of Hematology, Department of Medical and Surgical Science, University of Modena and Reggio Emilia, Modena, Italy. ^[5] Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA. ^[6]

主题词成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);苯并噻唑类(Benzothiazoles);药物协同作用(Drug Synergism);反馈, 生理(Feedback, Physiological);人类(Humans);吲哚类(Indoles);白血病, 髓样, 急性(Leukemia, Myeloid, Acute);中年人(Middle Aged);苯脲化合物(Phenylurea Compounds);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);磷酰化(Phosphorylation);蛋白质组(Proteome);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);吡咯类(Pyrroles);回顾性研究(Retrospective Studies);信号传导(Signal Transduction);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases);肿瘤细胞, 培养的(Tumor Cells, Cultured);青年人(Young Adult)

DOI 10.1038/leu.2014.123

PMID 24699302

发布时间 2023-11-20

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Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.

Leukemia

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Leukemia

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Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.

Leukemia

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Leukemia

相关期刊

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