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首页> Journal of affective disorders> Abnormality in serum levels of mature brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in mood-stabilized patients with bipolar disorder: a study of two independent cohorts.

Abnormality in serum levels of mature brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in mood-stabilized patients with bipolar disorder: a study of two independent cohorts.

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作者： Kristoffer,Södersten ^[1] ; Erik,Pålsson ^[2] ; Tamaki,Ishima ^[3] ; Keiko,Funa ^[4] ; Mikael,Landén ^[5] ; Kenji,Hashimoto ^[3] ; Hans,Ågren ^[2]

作者单位： Institute of Neuroscience and Physiology, Section of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg SE-416 85, Sweden. Electronic address: kristoffer.sodersten@gu.se. ^[1] Institute of Neuroscience and Physiology, Section of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg SE-416 85, Sweden. ^[2] Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, Chiba, Japan. ^[3] Sahlgrenska Cancer Center, University of Gothenburg, Gothenburg, Sweden. ^[4] Institute of Neuroscience and Physiology, Section of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg SE-416 85, Sweden; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. ^[5]

关键词 Biomarker Bipolar disorder Diagnosis Mature BDNF Serum proBDNF

主题词成年人(Adult);双相情感障碍(Bipolar Disorder);脑源性神经营养因子(Brain-Derived Neurotrophic Factor);病例对照研究(Case-Control Studies);队列研究(Cohort Studies);横断面研究(Cross-Sectional Studies);女(雌)性(Female);人类(Humans);男(雄)性(Male);基质金属蛋白酶9(Matrix Metalloproteinase 9);中年人(Middle Aged)

DOI 10.1016/j.jad.2014.01.009

PMID 24709015

发布时间 2018-12-02

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Journal of affective disorders

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