Engineered human lipocalin as an antibody mimetic: application to analysis of the small peptide hormone hepcidin.

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作者： Nicolai,Grebenchtchikov ^[1] ; Anneke J,Geurts-Moespot ^[1] ; Stefan,Trentmann ^[2] ; Nicole,Andersen ^[2] ; Rachida S,Bel Aiba ^[2] ; Andrea,Allersdorfer ^[2] ; Coby M,Laarakkers ^[1] ; Fred C,Sweep ^[1] ; Harold,Tjalsma ^[1] ; Andreas M,Hohlbaum ^[2] ; Dorine W,Swinkels ^[3]

作者单位： Department of Laboratory Medicine Laboratory of Genetic, Metabolic and Endocrine Diseases Radboud University Medical Centre Nijmegen, the Netherlands. ^[1] Pieris AG, Freising, Germany. ^[2] Department of Laboratory Medicine Laboratory of Genetic, Metabolic and Endocrine Diseases Radboud University Medical Centre Nijmegen, the Netherlands dorine.swinkels@radboudumc.nl. ^[3]

主题词抗体, 单克隆(Antibodies, Monoclonal);人类(Humans);脂笼蛋白质类(Lipocalins);分子模拟(Molecular Mimicry);蛋白质工程(Protein Engineering);底物特异性(Substrate Specificity)

DOI 10.1373/clinchem.2014.221671

PMID 24710076

发布时间 2019-07-22

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