The anti-promyelocytic leukemia mode of action of two endophytic secondary metabolites unveiled by a proteomic approach.-论文-万方医学网

作者： Margareth B C,Gallo ^[1] ; Miranda J S,Falso ^[2] ; Fernanda,Balem ^[3] ; Diego,Menezes ^[4] ; Núbia,Rocha ^[5] ; Raghavan,Balachandran ^[1] ; Timothy S,Sturgeon ^[6] ; Mônica T,Pupo ^[7] ; Billy W,Day ^[1]

作者单位： Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA. ^[1] Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA. ^[2] Department of Structural Biology, University of Pittsburgh, Pittsburgh, PA, USA. ^[3] Mass Spectrometry Core Facility, Centro de Pesquisas Gonçalo Moniz (CPqGM) - FIOCRUZ, Salvador, BA, Brazil. ^[4] Núcleo de Biotecnologia e Bioprospecção, Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil. ^[5] Center for Vaccine Research, University of Pittsburgh, Pittsburgh, PA, USA. ^[6] Department of Pharmaceutical Sciences, Faculdade de Ciências Farmacêuticas de Ribeirão Preto - USP, Ribeirão Preto, SP, Brazil. ^[7]

主题词 14-3-3蛋白质类(14-3-3 Proteins);抗肿瘤药(Antineoplastic Agents);阿非科林(Aphidicolin);菊科(Asteraceae);生物制品(Biological Products);细胞死亡(Cell Death);麦角固醇(Ergosterol);真菌(Fungi);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HL-60细胞(HL-60 Cells);人类(Humans);炎症(Inflammation);白血病, 早幼粒细胞, 急性(Leukemia, Promyelocytic, Acute);微管(Microtubules);线粒体(Mitochondria);氧化性应激(Oxidative Stress);蛋白质组(Proteome);蛋白质组学(Proteomics);胸腺素(Thymosin);微管蛋白(Tubulin)

DOI 10.1055/s-0034-1368301

PMID 24710897

发布时间 2016-11-25

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The anti-promyelocytic leukemia mode of action of two endophytic secondary metabolites unveiled by a proteomic approach.

Planta medica

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The anti-promyelocytic leukemia mode of action of two endophytic secondary metabolites unveiled by a proteomic approach.

Planta medica

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Planta medica

相关期刊

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