An international interpretation study using the ALK IHC antibody D5F3 and a sensitive detection kit demonstrates high concordance between ALK IHC and ALK FISH and between evaluators.
第一作者:
Murry W,Wynes
第一单位:
*Department of Medicine, Division of Medical Oncology, University of Colorado, Aurora, Colorado; †Department of Pathology Brigham and Women's Hospital, Boston, Massachusetts; ‡Institute of Pathology, Charité University Hospital Berlin, Germany; §Department of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, The Netherlands; ‖Princess Margaret Hospital, University Health Network, University of Toronto, Ontario, Canada; ¶Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Kanokoden, Chikusa-ku, Nagoya, Japan; #Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio; ** Department of Pathology, University of Colorado, Aurora, Colorado; and ††University of Colorado Comprehensive Cancer Center, Aurora, Colorado.
作者:
医学主题词
抗体(Antibodies);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);假阴性反应(False Negative Reactions);假阳性反应(False Positive Reactions);人类(Humans);免疫组织化学(Immunohistochemistry);原位杂交, 荧光(In Situ Hybridization, Fluorescence);肺肿瘤(Lung Neoplasms);观察者偏差(Observer Variation);受体蛋白质酪氨酸激酶类(Receptor Protein-Tyrosine Kinases);敏感性与特异性(Sensitivity and Specificity)
DOI
10.1097/JTO.0000000000000115
PMID
24722153
发布时间
2022-03-21
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