The A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits.

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作者： Nevi,Parameswaran ^[1] ; Benjamin G,Dewals ^[2] ; Tom C,Giles ^[3] ; Christopher,Deppmann ^[4] ; Martin,Blythe ^[5] ; Alain,Vanderplasschen ^[6] ; Richard D,Emes ^[7] ; David,Haig ^[8]

作者单位： School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington LE12 5RD, United Kingdom. Electronic address: nevi.parameswaran@googlemail.com. ^[1] Immunology-Vaccinology, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium. Electronic address: bgdewals@ulg.ac.be. ^[2] Advanced Data Analysis Centre, University of Nottingham, Sutton Bonington LE12 5RD, United Kingdom. Electronic address: tom.giles@nottingham.ac.uk. ^[3] Department of Biology, University of Virginia, Charlottesville, USA. Electronic address: deppmann@virginia.edu. ^[4] Centre for Genetics and Genomics, University of Nottingham, Nottingham, United Kingdom. Electronic address: martin.blythe@nottingham.ac.uk. ^[5] Immunology-Vaccinology, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium. Electronic address: a.vdplasschen@ulg.ac.be. ^[6] School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington LE12 5RD, United Kingdom; Advanced Data Analysis Centre, University of Nottingham, Sutton Bonington LE12 5RD, United Kingdom. Electronic address: richard.emes@nottingham.ac.uk. ^[7] School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington LE12 5RD, United Kingdom. Electronic address: david.haig@nottingham.ac.uk. ^[8]

关键词 Cytotoxicity Herpesvirus Malignant catarrhal fever Transcription regulation bZIP protein