Increased levels of fatty acids contributed to induction of hepatic CYP3A4 activity induced by diabetes - in vitro evidence from HepG2 cell and Fa2N-4 cell lines.
作者:
主题词
动物(Animals);细胞系(Cell Line);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);糖尿病, 实验性(Diabetes Mellitus, Experimental);酶诱导(Enzyme Induction);脂肪酸类(Fatty Acids);基因表达(Gene Expression);Hep G2细胞(Hep G2 Cells);肝细胞(Hepatocytes);人类(Humans);肝(Liver);RNA, 信使(RNA, Messenger);大鼠(Rats);链脲菌素(Streptozocin);增量调节(Up-Regulation)
DOI
10.1254/jphs.13212fp
PMID
24739263
发布时间
2019-09-11
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