Adjuvant bevacizumab in patients with melanoma at high risk of recurrence (AVAST-M): preplanned interim results from a multicentre, open-label, randomised controlled phase 3 study.

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作者： Pippa G,Corrie ^[1] ; Andrea,Marshall ^[2] ; Janet A,Dunn ^[2] ; Mark R,Middleton ^[3] ; Paul D,Nathan ^[4] ; Martin,Gore ^[5] ; Neville,Davidson ^[6] ; Steve,Nicholson ^[7] ; Charles G,Kelly ^[8] ; Maria,Marples ^[9] ; Sarah J,Danson ^[10] ; Ernest,Marshall ^[11] ; Stephen J,Houston ^[12] ; Ruth E,Board ^[13] ; Ashita M,Waterston ^[14] ; Jenny P,Nobes ^[15] ; Mark,Harries ^[16] ; Satish,Kumar ^[17] ; Gemma,Young ^[18] ; Paul,Lorigan ^[19]

作者单位： Cambridge Cancer Trials Centre, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK. Electronic address: pippa.corrie@addenbrookes.nhs.uk. ^[1] Warwick Clinical Trials Unit, University of Warwick, Coventry, UK. ^[2] Oxford National Institute for Health Research Biomedical Research Centre, Oxford, UK. ^[3] Medical Oncology, Mount Vernon Hospital, Northwood, Middlesex, UK. ^[4] Royal Marsden Hospital NHS Trust, London, UK. ^[5] Oncology Research, Broomfield Hospital, Chelmsford, UK. ^[6] Oncology Department, Leicester Royal Infirmary, Leicester, UK. ^[7] Sir Bobby Robson Cancer Trials Research Centre, Freeman Hospital, Newcastle upon Tyne, UK. ^[8] Cancer Research, St James's University Hospital, Leeds, UK. ^[9] Academic Unit of Clinical Oncology, Weston Park Hospital, Sheffield, UK. ^[10] Cancer and Palliative Care, St Helen's Hospital, St Helens, UK. ^[11] Oncology Department, Royal Surrey County Hospital, Surrey, UK. ^[12] Oncology Department, Royal Preston Hospital, Preston, UK. ^[13] Clinical Trials Unit, Beatson West of Scotland Cancer Centre, Glasgow, UK. ^[14] Clinical Oncology, Norfolk and Norwich University Hospital, Norwich, UK. ^[15] Guy's and St Thomas' Hospital, London, UK. ^[16] Velindre Cancer Centre, Cardiff, UK. ^[17] Cambridge Cancer Trials Centre/Cambridge Clinical Trials Unit-Cancer Theme, Addenbrooke's Hospital, Cambridge, UK. ^[18] Deptartment of Medical Oncology, Christie Hospital, Manchester, UK. ^[19]