The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis.

导出 OA

翻译打印收藏纠错

作者： Stephan,Laggai ^[1] ; Sonja M,Kessler ^[2] ; Stefan,Boettcher ^[3] ; Valérie,Lebrun ^[4] ; Katja,Gemperlein ^[5] ; Eva,Lederer ^[6] ; Isabelle A,Leclercq ^[4] ; Rolf,Mueller ^[5] ; Rolf W,Hartmann ^[7] ; Johannes,Haybaeck ^[6] ; Alexandra K,Kiemer ^[1]

作者单位： Department of Pharmacy, Pharmaceutical Biology, Department of Pharmacy, Pharmaceutical, Saarland University, Saarbrücken, Germany. ^[1] Department of Pharmacy, Pharmaceutical Biology, Department of Pharmacy, Pharmaceutical, Saarland University, Saarbrücken, Germany Medicinal Chemistry, Saarland University, Saarbrücken, Germany Laboratory of Hepato-gastroenterology, Institut de Recherche expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium. ^[2] Medicinal Chemistry, Saarland University, Saarbrücken, Germany. ^[3] Laboratory of Hepato-gastroenterology, Institut de Recherche expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium. ^[4] Department of Pharmacy, Pharmaceutical Biotechnology, Saarland University, Saarbrücken, Germany Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany. ^[5] Institute of Pathology, Medical University of Graz, Graz, Austria. ^[6] Medicinal Chemistry, Saarland University, Saarbrücken, Germany Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Saarbrücken, Germany. ^[7]

关键词 fatty acid elongase 6 hepatic steatosis insulin-like growth factor 2 signalling sterol regulatory element binding transcription factor 1