Drug analog inhibition of indoleamine 2,3-dioxygenase (IDO) activity modifies pattern recognition receptor expression and proinflammatory cytokine responses early during influenza virus infection.
第一作者:
Julie M,Fox
第一单位:
Department of Infectious Diseases, University of Georgia, Athens, Georgia, USA.
作者:
主题词
动物(Animals);细胞系(Cell Line);细胞因子类(Cytokines);酶诱导(Enzyme Induction);酶抑制剂(Enzyme Inhibitors);女(雌)性(Female);基因表达调控(Gene Expression Regulation);人类(Humans);吲哚胺-吡咯2,3-双加氧酶(Indoleamine-Pyrrole 2,3,-Dioxygenase);炎症(Inflammation);流感病毒A型, H3N2亚型(Influenza A Virus, H3N2 Subtype);肺(Lung);巨噬细胞活化(Macrophage Activation);巨噬细胞, 肺泡(Macrophages, Alveolar);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);核蛋白质类(Nuclear Proteins);正黏病毒科感染(Orthomyxoviridae Infections);受体, 模式识别(Receptors, Pattern Recognition);时间因素(Time Factors);色氨酸(Tryptophan);泛素蛋白连接酶类(Ubiquitin-Protein Ligases)
DOI
10.1189/jlb.3AB0114-046RR
PMID
24799604
发布时间
2021-10-21
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