Neurosteroids allopregnanolone sulfate and pregnanolone sulfate have diverse effect on the α subunit of the neuronal voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.7, and Nav1.8 expressed in xenopus oocytes.

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作者： Takafumi,Horishita ^[1] ; Nobuyuki,Yanagihara ; Susumu,Ueno ; Yuka,Sudo ; Yasuhito,Uezono ; Dan,Okura ; Tomoko,Minami ; Takashi,Kawasaki ; Takeyoshi,Sata

作者单位： From the Department of Anesthesiology (T.H., D.O., T.M., T.K., T.S.) and Department of Pharmacology (N.Y.), School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan; Department of Occupational Toxicology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan (S.U.); Department of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan (Y.S.); and Cancer Pathophysiology Division, National Cancer Center Research Institute, Tokyo, Japan (Y.U.). ^[1]

主题词动物(Animals);女(雌)性(Female);孕烷诺龙(Pregnanolone);受体, GABA-A(Receptors, GABA-A);光滑爪蟾(Xenopus laevis)

DOI 10.1097/ALN.0000000000000296

PMID 24809977

发布时间 2014-09-16

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