Phase II study evaluating the efficacy, safety, and pharmacodynamic correlative study of dual antiangiogenic inhibition using bevacizumab in combination with sorafenib in patients with advanced malignant melanoma.
第一作者:
Devalingam,Mahalingam
第一单位:
Institute for Drug Development, Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA, Mahalingam@uthscsa.edu.
作者:
医学主题词
血管生成抑制剂(Angiogenesis Inhibitors);抗肿瘤联合化疗方案(Antineoplastic Combined Chemotherapy Protocols);疾病恶化(Disease Progression);药物监测(Drug Monitoring);临床试验早期终止(Early Termination of Clinical Trials);可行性研究(Feasibility Studies);女(雌)性(Female);人类(Humans);高血压(Hypertension);动力学(Kinetics);男(雄)性(Male);黑色素瘤(Melanoma);中年人(Middle Aged);肿瘤分期(Neoplasm Staging);烟酰胺(Niacinamide);苯脲化合物(Phenylurea Compounds);蛋白激酶抑制剂(Protein Kinase Inhibitors);受体, 血管内皮生长因子(Receptors, Vascular Endothelial Growth Factor);疾病严重程度指数(Severity of Illness Index);血管内皮生长因子类(Vascular Endothelial Growth Factors)
DOI
10.1007/s00280-014-2479-8
PMID
24817603
发布时间
2018-12-02
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