Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearance of the conjugated metabolites.-论文-万方医学网

作者： Kan,Zhong ^[1] ; Xiuli,Li ^[1] ; Cen,Xie ^[1] ; Yifan,Zhang ^[1] ; Dafang,Zhong ^[1] ; Xiaoyan,Chen ^[2]

作者单位： Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. ^[1] Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China xychen@simm.ac.cn. ^[2]

主题词成年人(Adult);抗菌药(Anti-Bacterial Agents);曲线下面积(Area Under Curve);细胞系(Cell Line);西咪替丁(Cimetidine);女(雌)性(Female);HEK293细胞(HEK293 Cells);人类(Humans);输注, 静脉内(Infusions, Intravenous);肾(Kidney);男(雄)性(Male);中年人(Middle Aged);硝基咪唑类(Nitroimidazoles);有机阴离子转运蛋白1(Organic Anion Transport Protein 1);有机阴离子转运子, 非钠依赖(Organic Anion Transporters, Sodium-Independent);丙磺舒(Probenecid);蛋白质结合(Protein Binding);肾功能不全(Renal Insufficiency);转染(Transfection);青年人(Young Adult)

DOI 10.1128/AAC.02414-14

PMID 24820074

发布时间 2021-10-21

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Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearance of the conjugated metabolites.

Antimicrobial agents and chemotherapy

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Antimicrobial agents and chemotherapy

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Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearance of the conjugated metabolites.

Antimicrobial agents and chemotherapy

相似文献

Antimicrobial agents and chemotherapy

相关期刊

检索历史清除