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首页> Behavioural brain research> Environmental enrichment reduces methamphetamine cue-induced reinstatement but does not alter methamphetamine reward or VMAT2 function.

Environmental enrichment reduces methamphetamine cue-induced reinstatement but does not alter methamphetamine reward or VMAT2 function.

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作者： Rebecca S,Hofford ^[1] ; Mahesh,Darna ^[2] ; Carrie E,Wilmouth ^[1] ; Linda P,Dwoskin ^[2] ; Michael T,Bardo ^[3]

作者单位： Department of Psychology, University of Kentucky, Lexington, KY 40536, USA; Center for Drug Abuse Research Translation, University of Kentucky, Lexington, KY 40536, USA. ^[1] Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40536, USA; Center for Drug Abuse Research Translation, University of Kentucky, Lexington, KY 40536, USA. ^[2] Department of Psychology, University of Kentucky, Lexington, KY 40536, USA; Center for Drug Abuse Research Translation, University of Kentucky, Lexington, KY 40536, USA. Electronic address: mbardo@uky.edu. ^[3]

关键词 Conditioned place preference (CPP)Environmental enrichment Methamphetamine (METH)Self-administration Social isolation Vesicular monoamine transporter 2 (VMAT2)

主题词动物(Animals);条件反射, 操作式(Conditioning, Operant);提示(Cues);多巴胺摄取抑制剂(Dopamine Uptake Inhibitors);剂量效应关系, 药物(Dose-Response Relationship, Drug);环境(Environment);男(雄)性(Male);甲基苯丙胺(Methamphetamine);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);奖励(Reward);自我遵嘱服药(Self Administration);囊泡单胺转运蛋白质类(Vesicular Monoamine Transport Proteins)

DOI 10.1016/j.bbr.2014.05.007

PMID 24821405

发布时间 2021-10-21

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