In vivo genotoxicity of Ginkgo biloba extract in gpt delta mice and constitutive androstane receptor knockout mice.

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第一作者： Jun,Maeda

第一单位： Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan Division of Toxicology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.

作者： Jun,Maeda ^[1] ; Aki,Kijima ^[2] ; Kaoru,Inoue ^[2] ; Yuji,Ishii ^[2] ; Ryohei,Ichimura ^[2] ; Shinji,Takasu ^[2] ; Ken,Kuroda ^[2] ; Kohei,Matsushita ^[2] ; Yukio,Kodama ^[3] ; Naoaki,Saito ^[4] ; Takashi,Umemura ^[2] ; Midori,Yoshida ^[2]

作者单位： Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan Division of Toxicology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan. ^[1] Division of Pathology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan. ^[2] Laboratory of Molecular Pharmacology, Biosignal Research Center, Kobe University, Rokkodai-cho 1-1, Nada-ku, Kobe 657-8501, Japan. ^[3] Division of Toxicology, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan. ^[4]

关键词 Ginkgo biloba extract (GBE)comet assay constitutive androstane receptor (CAR)gene mutation assay genotoxicity micronucleus assay