Pre-clinical evaluation of [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 for imaging of insulinoma.

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作者： Ram Kumar,Selvaraju ^[1] ; Irina,Velikyan ^[2] ; Veronika,Asplund ^[3] ; Lars,Johansson ^[4] ; Zhanhong,Wu ^[5] ; Ivan,Todorov ^[5] ; Jack,Shively ^[5] ; Fouad,Kandeel ^[5] ; Barbro,Eriksson ^[6] ; Olle,Korsgren ^[7] ; Olof,Eriksson ^[3]

作者单位： Preclinical PET Platform (PPP), Department of Medicinal Chemistry, Uppsala University, SE-751 83 Uppsala, Sweden. Electronic address: ramkumar.selvaraju@pet.medchem.uu.se. ^[1] Preclinical PET Platform (PPP), Department of Medicinal Chemistry, Uppsala University, SE-751 83 Uppsala, Sweden; Department of Radiology, Oncology and Radiation Sciences, Uppsala University, SE-751 85 Uppsala, Sweden; PET Centre, Centre for Medical Imaging, Uppsala University Hospital, SE-751 85 Uppsala, Sweden. ^[2] Preclinical PET Platform (PPP), Department of Medicinal Chemistry, Uppsala University, SE-751 83 Uppsala, Sweden. ^[3] Department of Radiology, Oncology and Radiation Sciences, Uppsala University, SE-751 85 Uppsala, Sweden; AstraZeneca R&D, SE-431 83 Mölndal, Sweden. ^[4] Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA. ^[5] Department of Medical Sciences, Uppsala University Hospital, SE-751 85 Uppsala, Sweden. ^[6] Department of Immunology, Genetics and Pathology, Uppsala University, SE-751 85 Uppsala, Sweden. ^[7]

关键词 Glucagon like peptide-1 receptor (GLP-1R)Insulinoma Positron emission tomography (PET)[(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4