Bias due to lack of patient blinding in clinical trials. A systematic review of trials randomizing patients to blind and nonblind sub-studies.

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作者： Asbjørn,Hróbjartsson ^[1] ; Frida,Emanuelsson ^[2] ; Ann Sofia,Skou Thomsen ^[2] ; Jørgen,Hilden ^[2] ; Stig,Brorson ^[2]

作者单位： Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark, Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark and Department of Orthopaedic Surgery, Herlev University Hospital, Herlev, Denmark ah@cochrane.dk. ^[1] Nordic Cochrane Centre, Rigshospitalet, Copenhagen, Denmark, Department of Biostatistics, University of Copenhagen, Copenhagen, Denmark and Department of Orthopaedic Surgery, Herlev University Hospital, Herlev, Denmark. ^[2]

关键词 Bias blinding patient blinding randomized clinical trials systematic review

主题词双盲法(Double-Blind Method);人类(Humans);随机对照试验(主题)(Randomized Controlled Trials as Topic);单盲法(Single-Blind Method)

DOI 10.1093/ije/dyu115

PMID 24881045

发布时间 2022-04-08

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