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The preclinical Alzheimer cognitive composite: measuring amyloid-related decline.

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第一作者： Michael C,Donohue

第一单位： Division of Biostatistics and Bioinformatics, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla2Alzheimer's Disease Cooperative Study, Department of Neurosciences, University of California, San Diego, La Jolla.

作者： Michael C,Donohue ^[1] ; Reisa A,Sperling ^[2] ; David P,Salmon ^[3] ; Dorene M,Rentz ^[2] ; Rema,Raman ^[1] ; Ronald G,Thomas ^[3] ; Michael,Weiner ^[4] ; Paul S,Aisen ^[3] ; Australian Imaging, Biomarkers, and Lifestyle Flagship Study of Ageing ; Alzheimer’s Disease Neuroimaging Initiative ; Alzheimer’s Disease Cooperative Study

作者单位： Division of Biostatistics and Bioinformatics, Department of Family and Preventive Medicine, University of California, San Diego, La Jolla2Alzheimer's Disease Cooperative Study, Department of Neurosciences, University of California, San Diego, La Jolla. ^[1] Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston. ^[2] Alzheimer's Disease Cooperative Study, Department of Neurosciences, University of California, San Diego, La Jolla. ^[3] Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California5Department of Radiology, University of California, San Francisco. ^[4]

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);淀粉样β肽类(Amyloid beta-Peptides);载脂蛋白E4(Apolipoprotein E4);临床试验(主题)(Clinical Trials as Topic);认知障碍(Cognition Disorders);疾病恶化(Disease Progression);早期诊断(Early Diagnosis);执行功能(Executive Function);可行性研究(Feasibility Studies);女(雌)性(Female);杂合子(Heterozygote);人类(Humans);男(雄)性(Male);中年人(Middle Aged);神经心理学测验(Neuropsychological Tests);正电子发射断层显像术(Positron-Emission Tomography);前瞻性研究(Prospective Studies)

DOI 10.1001/jamaneurol.2014.803

PMID 24886908

发布时间 2022-04-09

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JAMA neurology

2014年71卷8期

961-70页

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The preclinical Alzheimer cognitive composite: measuring amyloid-related decline.

JAMA neurology

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The preclinical Alzheimer cognitive composite: measuring amyloid-related decline.

JAMA neurology

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JAMA neurology

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