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首页> Brain, behavior, and immunity> Reduced microglial immunoreactivity for endogenous NMDA receptor agonist quinolinic acid in the hippocampus of schizophrenia patients.

Reduced microglial immunoreactivity for endogenous NMDA receptor agonist quinolinic acid in the hippocampus of schizophrenia patients.

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作者： Tomasz,Gos ^[1] ; Aye-Mu,Myint ^[2] ; Kolja,Schiltz ^[3] ; Gabriela,Meyer-Lotz ^[4] ; Henrik,Dobrowolny ^[4] ; Stefan,Busse ^[4] ; Ulf J,Müller ^[4] ; Christian,Mawrin ^[5] ; Hans-Gert,Bernstein ^[4] ; Bernhard,Bogerts ^[3] ; Johann,Steiner ^[6]

作者单位： Department of Psychiatry, University of Magdeburg, Germany; Institute of Forensic Medicine, Medical University of Gdańsk, Gdańsk, Poland. ^[1] Department of Psychiatry, University of Magdeburg, Germany; Department of Psychiatry, University of Munich, Germany; School for Mental Health and Neuroscience, University of Maastricht, The Netherlands. ^[2] Department of Psychiatry, University of Magdeburg, Germany; Center for Behavioral Brain Sciences, Magdeburg, Germany. ^[3] Department of Psychiatry, University of Magdeburg, Germany. ^[4] Institute of Neuropathology, University of Magdeburg, Germany. ^[5] Department of Psychiatry, University of Magdeburg, Germany; Center for Behavioral Brain Sciences, Magdeburg, Germany. Electronic address: johann.steiner@med.ovgu.de. ^[6]

关键词 Glutamate Hippocampal formation Hippocampus Microglia Quinolinic acid Schizophrenia

主题词成年人(Adult);CA1区, 海马(CA1 Region, Hippocampal);细胞计数(Cell Count);兴奋性氨基酸激动剂(Excitatory Amino Acid Agonists);女(雌)性(Female);谷氨酸(Glutamic Acid);HLA-DR抗原(HLA-DR Antigens);海马(Hippocampus);人类(Humans);男(雄)性(Male);小神经胶质细胞(Microglia);中年人(Middle Aged);神经免疫调节(Neuroimmunomodulation);器官特异性(Organ Specificity);喹啉酸(Quinolinic Acid);受体, N-甲基-D-天冬氨酸(Receptors, N-Methyl-D-Aspartate);精神分裂症(Schizophrenia);突触传递(Synaptic Transmission)

DOI 10.1016/j.bbi.2014.05.012

PMID 24886967

发布时间 2014-09-16

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Brain, behavior, and immunity

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