New insights into the biological properties of Crocus sativus L.: chemical modifications, human monoamine oxidases inhibition and molecular modeling studies.

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作者： Celeste,De Monte ^[1] ; Simone,Carradori ^[2] ; Paola,Chimenti ^[1] ; Daniela,Secci ^[1] ; Luisa,Mannina ^[3] ; Francesca,Alcaro ^[4] ; Anél,Petzer ^[5] ; Clarina I,N'Da ^[5] ; Maria Concetta,Gidaro ^[4] ; Giosuè,Costa ^[4] ; Stefano,Alcaro ^[4] ; Jacobus P,Petzer ^[6]

作者单位： Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. ^[1] Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy. Electronic address: simone.carradori@uniroma1.it. ^[2] Dipartimento di Chimica e Tecnologie del Farmaco, Sapienza University of Rome, P.le A. Moro 5, 00185 Rome, Italy; Istituto di Metodologie Chimiche, Laboratorio di Risonanza Magnetica "Annalaura Segre", CNR, via Salaria km 29.300, 00015 Monterotondo, Rome, Italy. ^[3] Dipartimento di Scienze della Salute, "Magna Graecia" University of Catanzaro, Campus Universitario "S. Venuta", Viale Europa Loc. Germaneto, 88100 Catanzaro, Italy. ^[4] Pharmaceutical Chemistry and Centre of Excellence for Pharmaceutical Sciences, School of Pharmacy, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa. ^[5] Pharmaceutical Chemistry and Centre of Excellence for Pharmaceutical Sciences, School of Pharmacy, North-West University, Private Bag X6001, Potchefstroom 2520, South Africa. Electronic address: jacques.petzer@nwu.ac.za. ^[6]

关键词 Crocin Crocus sativus L.Depression Neurodegenerative disorders Safranal hMAO inhibitors