Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS.

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第一作者： Lan T H,Dang

第一单位： Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; The Heart and Stroke/Richard Lewar Centre of Excellence, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

作者： Lan T H,Dang ^[1] ; Nicole T,Feric ^[2] ; Carol,Laschinger ^[2] ; Wing Y,Chang ^[3] ; Boyang,Zhang ^[4] ; Geoffrey A,Wood ^[5] ; William L,Stanford ^[3] ; Milica,Radisic ^[6]

作者单位： Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; The Heart and Stroke/Richard Lewar Centre of Excellence, University of Toronto, Toronto, Ontario M5S 1A8, Canada. ^[1] Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada. ^[2] Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; Sprott Centre for Stem Cell Research, The Ottawa Hospital Research Institute, Ottawa, Ontario K1H 8L6, Canada; Department of Cellular & Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada. ^[3] Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario M5S 3E5, Canada. ^[4] Department of Pathobiology, University of Guelph, Guelph, Ontario N1G 2W1, Canada. ^[5] Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario M5S 3G9, Canada; The Heart and Stroke/Richard Lewar Centre of Excellence, University of Toronto, Toronto, Ontario M5S 1A8, Canada; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario M5S 3E5, Canada. Electronic address: m.radisic@utoronto.ca. ^[6]

关键词 Adhesion Angiopoietin-1 Apoptosis Human pluripotent stem cells Integrins QHREDGS