Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action.

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作者： P,Patrignani ^[1] ; S,Tacconelli ; E,Piazuelo ; L,Di Francesco ; M,Dovizio ; C,Sostres ; E,Marcantoni ; P,Guillem-Llobat ; P,Del Boccio ; M,Zucchelli ; C,Patrono ; A,Lanas

作者单位： Section of Cardiovascular and Pharmacological Sciences, Department of Neuroscience, Imaging and Clinical Science, Center of Excellence on Aging (CeSI), 'G. d'Annunzio' University, Chieti, Italy; Center of Excellence on Aging (CeSI), "G. d'Annunzio" University, Chieti, Italy. ^[1]

关键词 11-dehydro-thromboxane B2 acetylsalicylic acid antiplatelet drugs cyclooxygenase-1 proteomics thromboxane A2

主题词乙酰化作用(Acetylation);曲线下面积(Area Under Curve);阿司匹林(Aspirin);环氧化酶1(Cyclooxygenase 1);剂量效应关系, 药物(Dose-Response Relationship, Drug);血栓烷B2(Thromboxane B2)

DOI 10.1111/jth.12637

PMID 24942808

发布时间 2023-08-29

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准确一般字义偏差语意偏离译文作用小提交