Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways.
第一作者:
Sachin S,Rathod
第一单位:
National Centre for Cell Science, Pune, India.
作者:
关键词
Beta-cateninCNS, central nervous systemEGF, epidermal growth factorEMT, epithelial–mesenchymal transitionEV, empty vectorGBM, glioblastoma multiformeGIC, glioma initiating cellGSC, glioma stem cellGSK-3β, glycogen synthase kinase 3βGlioblastomaHeterogeneityMesenchymalNOD/SCID, nonobese diabetic/severe combined immunodeficiencyPARP, poly ADP-ribose polymerasesPDGFRA, platelet-derived growth factor receptor-αRictorTCGA, the cancer genome atlas databasebFGF, basic fibroblast growth factorqRT-PCR, quantitative real time PCR
DOI
10.1016/j.fob.2014.05.002
PMID
24944883
发布时间
2021-10-21
- 浏览87
FEBS open bio
485-95页
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