首页> Molecular and cellular endocrinology> Triazole GHS-R1a antagonists JMV4208 and JMV3002 attenuate food intake, body weight, and adipose tissue mass in mice.

Triazole GHS-R1a antagonists JMV4208 and JMV3002 attenuate food intake, body weight, and adipose tissue mass in mice.

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第一作者： M,Holubová

第一单位： Institute of Organic Chemistry and Biochemistry, AS CR, Prague, Czech Republic; Third Department of Medicine, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

作者： M,Holubová ^[1] ; V,Nagelová ^[2] ; Z,Lacinová ^[3] ; M,Haluzík ^[3] ; D,Sýkora ^[4] ; A,Moulin ^[5] ; A L,Blayo ^[5] ; J A,Fehrentz ^[5] ; J,Martinez ^[5] ; A,Stofkova ^[6] ; J,Jurčovičová ^[6] ; B,Zelezná ^[2] ; L,Maletínská ^[7]

作者单位： Institute of Organic Chemistry and Biochemistry, AS CR, Prague, Czech Republic; Third Department of Medicine, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic. ^[1] Institute of Organic Chemistry and Biochemistry, AS CR, Prague, Czech Republic. ^[2] Third Department of Medicine, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic. ^[3] Institute of Chemical Technology, Department of Analytical Chemistry, Prague, Czech Republic. ^[4] IBMM UMR 5274, CNRS - Universités Montpellier 1- Montpellier 2, Faculté de Pharmacie, Montpellier, France. ^[5] Department of Normal, Pathological and Clinical Physiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic. ^[6] Institute of Organic Chemistry and Biochemistry, AS CR, Prague, Czech Republic. Electronic address: maletin@uochb.cas.cz. ^[7]

关键词 Diet-induced obesity Food intake GHS-R1a antagonists JMV3002 JMV4208 Male C57BL/6 mice