TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease.-论文-万方医学网

作者： Yang-Lin,Liu ^[1] ; Helen L,Reeves ^[2] ; Alastair D,Burt ^[3] ; Dina,Tiniakos ^[1] ; Stuart,McPherson ^[1] ; Julian B S,Leathart ^[1] ; Michael E D,Allison ^[4] ; Graeme J,Alexander ^[4] ; Anne-Christine,Piguet ^[5] ; Rodolphe,Anty ^[6] ; Peter,Donaldson ^[1] ; Guruprasad P,Aithal ^[7] ; Sven,Francque ^[8] ; Luc,Van Gaal ^[8] ; Karine,Clement ^[9] ; Vlad,Ratziu ^[9] ; Jean-Francois,Dufour ^[5] ; Christopher P,Day ^[1] ; Ann K,Daly ^[3] ; Quentin M,Anstee ^[3]

作者单位： Institute of Cellular Medicine, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. ^[1] Northern Institute for Cancer Research, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. ^[2] 1] Institute of Cellular Medicine, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK [2]. ^[3] Liver Unit, Department of Medicine, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. ^[4] University Clinic of Visceral Surgery and Medicine, Inselspital Bern, 3010 Bern, Switzerland. ^[5] 1] Institute of Cellular Medicine, The Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK [2] Institut National de la Santé et de la Recherche Médicale (INSERM), U1065, Team 8, Nice F-06204, Cedex 3, France. ^[6] NIHR Nottingham Digestive Diseases Biomedical Research Unit, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, UK. ^[7] Department of Endocrinology, Diabetology and Metabolism, Antwerp University Hospital, Wilrijkstraat 10, B-2650 Edegem, Antwerp, Belgium. ^[8] Institute of Cardiometabolism and Nutrition, Pitié-Salpêtrière Hospital, 75013 Paris, France. ^[9]

主题词成年人(Adult);老年人(Aged);等位基因(Alleles);硫酸软骨素蛋白聚糖类(Chondroitin Sulfate Proteoglycans);队列研究(Cohort Studies);疾病恶化(Disease Progression);女(雌)性(Female);疾病遗传易感性(Genetic Predisposition to Disease);基因型(Genotype);杂合子(Heterozygote);人类(Humans);外源凝集素类, C型(Lectins, C-Type);肝(Liver);肝硬化(Liver Cirrhosis);男(雄)性(Male);膜蛋白质类(Membrane Proteins);中年人(Middle Aged);神经组织蛋白质类(Nerve Tissue Proteins);神经聚糖(Neurocan);多态性, 单核苷酸(Polymorphism, Single Nucleotide)

DOI 10.1038/ncomms5309

PMID 24978903

发布时间 2021-12-03

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TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease.

Nature communications

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TM6SF2 rs58542926 influences hepatic fibrosis progression in patients with non-alcoholic fatty liver disease.

Nature communications

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Nature communications

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