The interaction of mefloquine hydrochloride with cell membrane models at the air-water interface is modulated by the monolayer lipid composition.

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作者： Thiago Eichi,Goto ^[1] ; Luciano,Caseli ^[2]

作者单位： Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of Sao Paulo, Diadema, SP, Brazil. ^[1] Institute of Environmental, Chemical and Pharmaceutical Sciences, Federal University of Sao Paulo, Diadema, SP, Brazil. Electronic address: lcaseli@unifesp.br. ^[2]

关键词 Antiparasitic drug DODAB DPPC DPPG Langmuir monolayers Malaria Mefloquine hydrochloride PM-IRRAS Stearic acid

主题词抗疟药(Antimalarials);细胞膜(Cell Membrane);甲氟喹(Mefloquine);膜, 人工(Membranes, Artificial);单室脂质体(Unilamellar Liposomes)

DOI 10.1016/j.jcis.2014.05.050

PMID 24980622

发布时间 2014-08-12

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