Stabilization of human telomeric G-quadruplex and inhibition of telomerase activity by propeller-shaped trinuclear Pt(II) complexes.
第一作者:
Cui-Xia,Xu
第一单位:
MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou, Guangdong, 510275 (China), Fax: (+86) 20-84112245.
作者:
医学主题词
剂量效应关系, 药物(Dose-Response Relationship, Drug);酶抑制剂(Enzyme Inhibitors);荧光共振能量转移(Fluorescence Resonance Energy Transfer);G四链体(G-Quadruplexes);人类(Humans);分子结构(Molecular Structure);有机铂化合物(Organoplatinum Compounds);构效关系(Structure-Activity Relationship);表面等离激元(Surface Plasmon Resonance);末端转移酶端粒(Telomerase);端粒(Telomere)
DOI
10.1002/asia.201402258
PMID
24996049
发布时间
2014-08-26
- 浏览15
Chemistry, an Asian journal
2519-26页
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