Concerted all-or-none subunit interactions mediate slow deactivation of human ether-à-go-go-related gene K+ channels.

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第一作者： Steven J,Thomson

第一单位： From the Nora Eccles Harrison Cardiovascular Research and Training Institute and.

作者： Steven J,Thomson ^[1] ; Angela,Hansen ^[1] ; Michael C,Sanguinetti ^[2]

作者单位： From the Nora Eccles Harrison Cardiovascular Research and Training Institute and. ^[1] From the Nora Eccles Harrison Cardiovascular Research and Training Institute and Department of Internal Medicine and Division of Cardiovascular Medicine, University of Utah, Salt Lake City, Utah 84112 sanguinetti@cvrti.utah.edu. ^[2]

关键词 Biophysics Cooperativity Gating Potassium Channel hERG

主题词动物(Animals);快速延迟整流钾通道(Ether-A-Go-Go Potassium Channels);基因沉默(Gene Silencing);人类(Humans);动力学(Kinetics);突变(Mutation);光滑爪蟾(Xenopus laevis)

DOI 10.1074/jbc.M114.582437

PMID 25008322

发布时间 2021-10-21

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准确一般字义偏差语意偏离译文作用小提交