Recombinant Human Keratinocyte Growth Factor Induces Akt Mediated Cell Survival Progression in Emphysematous Mice.
作者:
主题词
动物(Animals);细胞凋亡(Apoptosis);半胱氨酸天冬氨酸蛋白酶9(Caspase 9);细胞存活(Cell Survival);疾病模型, 动物(Disease Models, Animal);药物评价, 临床前(Drug Evaluation, Preclinical);成纤维细胞生长因子7(Fibroblast Growth Factor 7);基因表达调控(Gene Expression Regulation);人类(Humans);滴注, 药物(Instillation, Drug);肺(Lung);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);PTEN磷酸水解酶(PTEN Phosphohydrolase);胰弹性蛋白酶(Pancreatic Elastase);磷酸肌醇3-激酶类(Phosphatidylinositol 3-Kinases);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);肺气肿(Pulmonary Emphysema);RNA, 信使(RNA, Messenger);随机分配(Random Allocation);重组蛋白质类(Recombinant Proteins);信号传导(Signal Transduction);血管内皮生长因子A(Vascular Endothelial Growth Factor A);血管内皮生长因子受体2(Vascular Endothelial Growth Factor Receptor-2);bcl相关死亡蛋白质(bcl-Associated Death Protein)
DOI
10.1016/j.arbres.2014.04.019
PMID
25017817
发布时间
2016-11-25
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